Titlu: | Instrumental assessment of the calming efficacy after induction of sun erythema. |
Obiective: | To assess the soothing efficacy of a product versus a reference product after repeated application to skin previously exposed to UV radiation. |
Planificare: | Duration of the study: 8 days. Beginning: 3 weeks upon receipt of the samples. Report: 3 weeks after the end of the study. |
Metodologie: | Colorimetric measurement with Chromameter® or Mexameter® or Colorimeter® of the erythematous skin reaction (non immunological reaction) induced by a short UVB exposure and evolution over the time after product application. |
Procedura: | • Previous determination of the minimal erythemal dose MED (less than 8 days before the beginning of the study). • Basal colorimetric measurements on the experimental sites (2 test sites and 1 control site). • UV exposure (2 MED) of the experimental sites. • Application of each product at the investigating centre for 4 consecutive days. • Daily colorimetric measurements on UV spots and adjacent sites on each experimental site (test and control) for 4 consecutive days. • Statistical comparis on of the results obtained before and after treatment for each product, at each experimental time. Optional: Additional controls |